对近30年芫花甘草同方配伍的文献进行了回顾性调查与分析,并对基层医院近3年78 238首处方调查。发现芫花甘草配伍临床应用少,实验研究多。文献报导仅有坠胎、冻疮、哮喘3种疾病,基层调研仅有3首处方。实验研究从最早的观察临床症状体征到细胞色素酶与液相色谱,研究逐渐深入。十八反药物配伍研究可以从古代文献数据挖掘与现代实验研究相结合,并借鉴其他反药的研究方法,为临床安全用药提供依据。
Through review and analysis of literature in 30 recent years and investigating 78 238 copies of prescription from local hospitals intresent three years.It was found that compatibility of Flos Genkwa and Radix Glycytthizae was seldom applied in clinical application and there were more reports on experimental research.Literature reports limited in three kinds of diseases like miscarrying,chilblain,asthma and three prescription.Experimental studies concerned observing of clinical signs and symptoms and cytochromes enzymes and liquid chromato graphy.Ancient literature and modern experimental research can provide evidence for safe application in clinical practice.