中文摘要：

目的 分析呼吸内科呼吸机相关肺炎（VAP）发生的危险因素.方法 选择解放军第九四医院2008年8月～2013年6月使用呼吸机治疗的患者191例,分析并比较VAP在年龄、性别、呼吸机使用时间、慢性阻塞性肺疾病、气管切开情况、意识状态等因素间的分布情况;采用Logistic回归分析对VAP发生的危险因素进行分析.结果 ①发生VAP的患者共17例,发生率为8.9％.②VAP发生率在年龄（≥60岁、＜60岁）[13.2％（10/76）、6.1％（7/115）]、呼吸机使用时间（≥7d、＜7 d）[14.5％ （9/62）、6.2％ （8/129）]、慢性阻塞性肺疾病（是、否）[18.8％（3/16）、8.0％（14/175）]等因素间进行比较,差异均有统计学意义（P＜0.05）;VAP发生率在性别、气管切开、意识状态等因素间比较,差异无统计学意义（P＞0.05）.③年龄≥60岁（OR =2.218）、呼吸机使用时间≥7d（OR=6.326）、合并慢性阻塞性肺疾病（OR=5.575）与VAP发生相关（P＜0.05）.结论 呼吸机治疗时间、年龄、合并慢性阻塞性肺疾病等情况与VAP的发生密切相关,应针对上述危险因素进行预防防治.

英文摘要：

Objective To analyze the risk factors of occurrence of ventilator-associated pneumonia （VAP） in patients with respiration medicine.Methods 191 patients with breathing machine treatment from August 2008 to June 2013 in the 94th Hospital of China People＇s Liberation Army were selected,the distributed situation of VAP in the elements of age,gender,breathing machine time,chronic obstructive pulmonary disease,conscious state,tracheotomy situation were analyzed and compared; Logistic analysis of regression was used to analyze the relative factors of VAP.Results ①17patients with VAP were found and the occurrence rate was 8.9％.②The difference of VAP occurrence rate in the elements of age （≥60 years,＜60 years） [13.2％ （10/76）,6.1％ （7/115）],breathing machine time （≥7 d,＜7 d） [14.5％ （9/62）,6.2％ （8/129）],chronic obstructive pulmonary disease （yes,no） [18.8％ （3/16）,8.0％ （14/175）],were statistically significant （P ＜ 0.05）; the difference of postoperative psychonosema rate in the elements of gender,tracheotomy,conscious state were not statistically significant （P ＞ 0.05）.③Age ≥60 years （OR =2.218,P ＜ 0.05）,breathing machine time ≥7 d （OR =6.326）,chronic obstructive pulmonary disease （OR =5.575） were found had correlation with postoperative VAP according to the Logistic analysis of regression （P ＜ 0.05）.Conclusion Age,breathing machine time,chronic obstructive pulmonary disease are risk factors of VAP.It is right to take prevention to the risk factors.