中文摘要：

（±）-galbulin和（±）-8，8＇-epi-aristoligone属于苯代四氢萘型木脂素类化合物，具有广泛的生物活性.以3，4-二甲氧基苯乙酸为起始原料，采用Horner-Wadsworth-Emmons反应和Friedel-Crafts反应为关键步骤，经8步得到了（±）-galbulin，并通过将（±）-galbulin苄位氧化得到（±）-8，8＇-epi-aristoligone.该法操作简单，路线较短，为苯代四氢萘型木脂素化合物的合成提供了参考.

英文摘要：

（±）-Galbulin and （±）-8,8＇-epi-aristoligone belong to cyclolignan family, and exhibit varieties of bioactivities. Using Horner-Wadsworth-Emmons and Friedel-Crafts reactions as key steps, galbulin has been successfully synthesized in eight steps from 3,4-dimethoxy-phenylacetic acid, and （±）-8,8＇-epi-aristoligone was obtained by oxidation of （±）-galbulin. The method is simple and easy to operate, which provides a reference for the synthesis of cyclolignan compounds.