目的证实CTA—MIP得到的侧枝循环评分与急性大脑中动脉闭塞患者临床预后的相关性,从而为此类患者的早期诊断及治疗决策提供新的依据。方法回顾性分析115例大脑中动脉M1段急性闭塞的脑梗死患者。根据CTA—MIP对其患者侧枝循环评分;根据90d的mRS分为预后好组(mRS≤2)和预后差组(mRS〉2)。利用多因素逻辑回归分析,判定侧枝循环状态与临床预后的关系。结果115例患者中57例预后好,58例预后差。基线期的NIHSS评分(P=0.001)和年龄(P=0.038)是预后的独立预测因素。女性患者的预后相对较好(P=0.003)。侧枝循环评分可以预测患者的转归,超过2分者预后多数好(P=0.023)。结论对于急性缺血性脑卒中患者,可通过CTA急诊获得侧枝循环状态,间接推断半暗带的信息,评估患者预后。
Objective To investigate the relationship between the collateral flow score conducted by CTA-MIP and clinical outcome of acute Ml-segment MCA occlusion. Methods 115 patients with acute cerebral infarction caused by the occlusion of Ml-segment MCA were included in this study. Accessed their collateral flow score by CTA-MIP. The patients were divided into 2 groups according to the clinical outcome:Good outcome with 90 days mRS ~〈2,bad outcome with 90 days mRS 〉 2. Analyze the correlation between collateral flow score and clinical outcome by multi-variables logistic regression a- nalysis. Result Of 115 eased included,57 with good outcome and 58 with bad outcome. Baseline NIHSS (P = 0. 001 ) , gender (P = 0. 003 ) and age (P = 0. 038) are the most important predictors of clinical outcome. Conclusions CTA-MIP can access collateral flow score of infarct brain in a few minutes, which may implicate the information about penumbra. With collateral flow score, we can predict the clinical outcome of acute cerebral infarction and make a better treatment decision.