目的:观察经皮穴位电刺激治疗原发性痛经的疗效。方法:将124例患者随机分为西药组、经皮穴位电刺激组,治疗3个月经周期,分别通过观察治疗前、治疗后1、2、3个月经周期的疗效及视觉疼痛模拟评分(VAS评分),并测定两组患者治疗前后血浆中前列腺素PGF2a、PGE2a含量以及PGF2a/PGE2a比值。结果:与治疗前相比,西药组与经皮电刺激组均可以降低VAS评分(P〈0.05),降低PGF2a含量,增加PGE2a含量以及降低PGF2a/PGE2a比值(P〈0.05);与西药组相比,经皮穴位电刺激组愈显率明显增加(P〈0.05),VAS评分在治疗后3个周期也明显降低(P〈0.05),PGF2a/PGE2a比值明显降低(P〈0.05)。结论:经皮穴位电刺激可以调节原发性痛经患者血浆PGF2a与PGE2a含量,且对原发性痛经患者具有明显效果,并优于西药治疗。
Objective: To observe the efficacy of transcutaneous electrical acupoint stimulation in the treatment of primary dysmenorrhea. Methods: 124 patients were randomly divided into medicine group and transcutaneous electrical acupoint stimulation group (TAES group), all of them treated three menstrual cycles. The twogroups of patients were observed the efficacy of 1, 2, or 3 of the menstrual cycle and visual analog scales (VAS score), and measured in plasma PGF2a, PGE2a content and PGF2a/PGE2a before and after treatment. Results:Compared with before treatment, medicine group and TAES group all reduced VAS scores (P〈0.05), reduced PGF2a content, increased PGE2a content and reduced PGF2a/PGE2a ratio (P〈0.05). Compared with the medicinegroup, Phase markedly effective rate of TAES group increased significantly (P〈0.05), the VAS score was significantly reduced after treatment three cycles (P〈0.05), and PGF2a/PGE2a ratio was significantly lower (P〈0.05).Conclusion: TAES could adjust the the plasma of PGF2a and PGE2a content, and had the obvious effect in patients with primary dysmenorrhea, TAES was better than medicine treatment.