中文摘要：

作为预防和治疗各种流感的首选药物,达菲的合成受到化学合成工作者的广泛关注.4年来,涌现出了多条极具特色的合成路线,将对这些合成路线做一综述.

英文摘要：

Tamiflu, one of the most common orally drugs for the treatment and prevention of influenza, has attracted exten- sive interests of synthetic chemists all over the world. Concise, efficient, and scalable synthetic approaches toward this mole- cule have been a very active field in recent years, and many diverse synthetic routes have been developed to date. In this re- view, representative synthetic routes employing chiral starting material or catalytic asymmetric reactions are briefly summa- rized.