中文摘要：

采用人工土壤培养法，通过14d急性暴露试验，研究了全氟辛烷磺酸（PFOS）对赤子爱胜蚓（Eiseniaafetida）的死亡率、谷胱甘肽硫转移酶（GST）和过氧化氢酶（CAT）活性以及DNA损伤的影响。研究结果表明：PFOS对蚯蚓14d-LC50为478．0mg·kg^-1，显示为低毒；急性暴露期间，PFOS显著抑制蚯蚓生长，生长抑制率随着PFOS浓度增加而增大，且有良好的剂量效应关系（r=0．951,P〈0．01）；PFOS对蚯蚓GST和CAT活性均没有显著性影响，没有观察到剂量效应关系；PFOS可致蚯蚓体腔细胞DNA损伤。不同浓度的PFOS对蚯蚓体腔细胞尾长、尾部DNA含量和尾矩的影响具有一定的剂量效应关系妒〈0．01），与对照组之间存在显著性差异（P〈0．05）。上述结果表明，PFOS对蚯蚓的存活影响显示为低毒，但是对生长有一定影响，可致蚯蚓体腔细胞DNA损伤。

英文摘要：

Artificial soil method was applied to study the effects of perfluorooctane sulfonate （PFOS） on earthworms （Eiseniafetida） during 14 d exposure. Survival, activities of glutathione S-transferase （GST）, cata- lase （CAT） and DNA damages of earthworms were detected. The results showed that 14 d-LC50 was 478.0 mg· kg^-11, indicating low toxicity;PFOS significantly inhibited the growth of earthworms during acute exposure, and the growth inhibition rates increased with the increase of PFOS concentration, showing dose-response re- lationship （r=0.951,P 〈0.01）. Neither GST nor CAT activity showed dose-response relationship with PFOS concentration; DNA damages of earthworm coelomocytes were detected after 14 d exposure to PFOS. Tail length （TL）, tail DNA content （TD） and tail moment （TM） values not only exhibited a significant difference （P 〈0.05） compared with the control, but also had a strong dose-response relationship （P 〈0.01）. In conclusion, PFOS had a low toficity effect on survival of earthworms; however, it could inhibit the growth, and damagethe coelomocytes DNA of earthworms.