目的 研究纳米氧化铁颗粒在工作场所中的暴露特征.方法 选取某纳米氧化铁生产企业,检测不同工作地点纳米颗粒物的实时数量浓度、表面积浓度和质量浓度,对采集的颗粒物进行形态学和元素成分分析.结果 各检测点平均数量和表面积浓度分别为黄粉(α-Fe2O3· nH2O)粉碎(16 566pt/cm3,106.082μm2/cm3)、包装(12 386 pt/cm3,89.861μm2/cm3)、装运点(13 808 pt/cm3,102.071μm2/cm3)、成品储存室(17 192 pt/cm3,115.044 μm2/cm3),与车间空白(11 420 pt/cm3,85.026 μm2/cm3)比较,差异均有统计学意义(P<0.05);数量浓度和表面积浓度高度相关(r=0.784);数量浓度、表面积浓度均与质量浓度低度相关(r1=0.323,r2=0.331);扫描电镜显示纳米氧化铁颗粒呈纺锤状;铁(Fe)的重量百分比占所采集颗粒物化学成分的19.33%.结论 黄粉粉碎和成品储存室的纳米颗粒暴露浓度较高,主要是纳米氧化铁颗粒;数量浓度与表面积浓度间具有高度相关关系.
Objective To investigate the characteristics of exposure to iron oxide nanoparticles in workplace.Methods The real-time particle number (NC),surface area (SAC),and mass (MC) concentrations of nanoparticles were measured in various locations of a selected workplace manufacturing iron oxide nanoparticles.The collected particles were analyzed for morphology and elemental composition.Results The average NCs and SACs in milling site (16 566 pt/cm3,106.082 μm2/cm3),packaging site (12 386 pt/cm3,89.861 μm2/cm3),shipping site (13 808 pt/cm3,102.071 μm2/cm3),and product storage room (17192 pt/cm3,115.044 μm2/cm3) of the yellow powder (α-Fe2O3·nH2O) were all significantly higher than the workplace background concentrations (11 420 pt/cm3,85.026 μm2/cm3) (all P〈0.05).The NC was highly correlated with the SAC (r=0.784),while both NC and SAC were loosely correlated with the MC (r1=0.323,r2=0.331).Scanning electron microscopy revealed a spindle-like shape of the iron oxide nanoparticle;the chemical composition of the collected particles contained 19.33 weight percent iron (Fe).Conclusion The milling site and product storage room of the yellow powder are exposed to a higher concentration of nanoparticles,which are mainly composed of iron oxide nanoparticles.The NC is highly correlated with the SAC.