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中文摘要：
目的将建立人的骨肉瘤肺转移的一个裸体老鼠模特儿。人的骨肉瘤房间潜水艇线 M8 和 M6 的生长被 MTT 试金决定的方法。2 × 107 个房间被注入裸体老鼠的尾巴静脉。老鼠被牺牲在在注射以后的星期 4 上开始了，并且肺转移在宏观、显微镜的观察下面被评估与他染色。结果低变形的潜水艇线 M6 的生长比高度变形的潜水艇线 M8 低。在注射 M8 以后的十七只老鼠发生了肺转移当仅仅一只老鼠发生在 M6 时组。而且，在转移以内的 M8 房间是有可变原子着色过度的安排混乱。一只老鼠为人的骨肉瘤癌症肺转移建模的结论能被注射建立进尾巴静脉的转移 MG63 房间的不同能力。
英文摘要：
Objective： To establish a nude mice model of human osteosarcoma lung metastasis. Methods： The growth of human osteosarcoma cell sublines M8 and M6 was determined by MTT assay. 2 × 10^7 cells were injected into the tail vein of nude mice. Mice were sacrificed started on week 4 after injection, and lung metastases were evaluated under both macroscopic and microscopic observation with HE staining. Results： The growth of low-metastatic subline M6 was lower than high-metastatic sublines M8. Seventeen mice after injected M8 had occurred lung metastases while only one mice had occurred in M6 group. Moreover, M8 cells within metastases were arrangement disorder with variable nuclear hyperchromasia. Conclusion： A mouse model for human osteosarcoma cancer lung metastasis can be established by injection different ability of metastasis MG63 cells into tail vein.
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