中文摘要：

目的通过对比单孔腹腔镜和标准腹腔镜下肾部分切除术的临床疗效,探讨单孔腹腔镜肾部分切除术的手术特点及其安全性、可行性和优缺点。方法 2009年8月至2015年2月同一手术组完成的12例单孔腹腔镜肾部分切除术,选择手术日期相近、肿瘤大小和DAP评分类似、进行标准腹腔镜肾部分切除术的患者22例作为对照组,回顾性分析两组患者的临床资料,比较临床疗效。结果两组共34例患者均顺利完成手术,无中转开放手术。两组患者的体质量指数、肿瘤大小、DAP评分差异均无统计学意义（P〉0.05）。单孔组和标准腹腔镜组术后肠道恢复时间分别为（1.50±0.71）d和（2.45±0.96）d,疼痛评分分别为3.5±1.2和4.3±0.9,切口满意度评分分别为8.1±1.8和7.2±2.1,差异均有统计学意义（P〈0.05）;手术时间分别为（213.1±33.9）min和（208.5±65.7）min,术中出血量分别为（92.7±66.8）mL和（162.3±168.1）mL、热缺血时间分别为（20.5±12.8）min和（19.5±7.5）min,差异均无统计学意义（P〉0.05）。术前和术后1个月分别采用99mTc-DTPA测定双肾肾小球滤过率（GFR）,单孔组和标准腹腔镜组患肾术后GFR较术前分别下降（3.7±8.6）mL/min和（8.9±10.1）mL/min,差异无统计学意义（P〉0.05）。结论单孔多通道腹腔镜肾切除术安全、有效,对于肿瘤直径较小、位置较好的肾肿瘤的治疗效果与标准腹腔镜相似。

英文摘要：

Objective To compare the clinical outcomes of laparoendoscopic single-site（LESS）and traditional standard laparoscopy partial nephrectomy surgery,so as to investigate the characteristics,safety,feasibility,advantages and disadvantages of LESS nephrectomy surgery. Methods The same surgical group completed 12 cases of LESS partial nephrectomy from August 2009 to February 2015;22cases who received standard laparoendoscopic partial nephrectomy in the same period served as controls;two groups had similar tumor size and DAP scores.The clinical data were retrospectively analyzed to compare the clinical efficacies of the two groups.Results All procedures were completed successfully without conversion to open cases in the two groups.The body mass index,tumor size or DAP scores were not statistically different between the both groups（P〉0.05）.The bowel recovery time,pain score,and cutouts satisfaction scores of LESS group were significantly different between the two groups（[1.50±0.71]d vs[2.45±0.96]d,3.5± 1.2vs 4.3±0.9,and 8.1±1.8vs7.2±2.1,P〈0.05）.The operation time,blood loss,and warm ischemia time of LESS group were not significantly different from those of the standard group（[213.1± 33.9]min vs[208.5± 65.7]min,[92.7± 66.8]mL vs[162.3±168.1]mL,and[20.5±12.8]min vs[19.5±7.5]min,P〉0.05）.The renal glomerular filtration rate（GFR）was measured with 99 mTcDTPA before and 1month after the operation,and the GFR of LESS and standard laparoendoscopic groups had a decrease of（3.7±8.6）mL/min and（8.9±10.1）mL/min,respectively,showing no significant difference（P〉0.05）.Conclusion The LESS nephrectomy is safe and effective,which has a similar outcome with standard laparoendoscopic partial nephrectomy whenthe tumor is small and in a good position.