中文摘要：

以取代的芳香醛和乙酰丙酸乙酯为原料,通过Knoevenagel缩合、亲核加成、环合、脱水等过程,快速高效地合成了8种未见文献报道的3-[2-取代芳基-1,5-苯并二氮杂-4-基]丙酸乙酯化合物。通过1H NMR、13C NMR、IR、MS和X射线单晶体衍射确定了目标产物的结构,对合成目标化合物的反应条件进行了较详细的研究,并提出了可能的反应机理。

英文摘要：

Eight novel compounds of 3-[2-Substituted Aryl-1,5-Benzodiazepin-4-yl]propionate were efficiently synthesized by the Knoevenagel reaction,nucleophilic addition reaction and dehydration cyclization reaction,using substituted aromatic aldehyde and ethyl levulinate as starting material. The structures of these compounds were determined by1 H NMR,13 C NMR,IR,MS and X-ray single crystal diffraction. The exhaustive researches on the synthetic reaction of the class of compounds were carried out,and the reaction mechanism has been unequivocally established in this paper.