目的:通过观察虚燥更平颗粒对女性高血压病(围绝经期)生活质量的影响,从而为中医治疗女性高血压病(围绝经期)提供临床依据。方法:收集2008年7月至2009年10月新疆医科大学附属中医医院高血压科就诊的阴虚内燥证女性高血压病(围绝经期)患者96例(病房59例、门诊37例),随机分为治疗组与对照组,两组在西药基础上,分别给予虚燥更平颗粒及模拟剂,疗程为8周,分别于治疗前与治疗后2、4、8周各进行1次生活质量评分、中医证候评分,并做统计分析。结果:①治疗组生理状态、躯体化症状、性功能失调、睡眠状态、生气或活力、焦虑、压抑等状态积分均较对照组增高(P〈0.05),而强迫状态积分无统计学差异。②治疗组烘热汗出、烦躁易怒、眩晕头昏、口干舌燥、失眠心悸、健忘、手或足心热、忧郁寡欢、腰膝酸痛、手或足麻木等症候积分均较对照组降低(P〈0.05),而耳鸣症候积分无统计学差异;中医证候疗效总有效率高于对照组(P〈0.05)。结论:应用虚燥更平颗粒治疗女性高血压病(围绝经期)患者,可以提高生活质量,同时能有效改善其临床症状。
Objective: To observe the effect of the Xuzao Gengping Granule on the quality of females’ life and all the females with climacteric hypertension,providing the clinical basis for the traditional Chinese medicine to cure female hypertensive disease(menopause).Methods: 96 patients with female climacteric hypertension were choose from hypertension outpatient clinics and ward in Chinese Medicine Hospital of Xinjiang Uygur Autonomous Region between July 2008 and October 2009,the Yinxu Neizao group was divided into treatment group and control group.To judge the score of the quality of life and TCM syndrome respectively before and after treatment.Results: ① Compared with the control group,the score of physiological status,somatization symptoms,sexual dysfunction,sleep and other state points in treatment group were significantly higher than the control group(P〈0.05),while the points of forcing state did not have statistically significant;② the score of bake thermal sweating,irritability,dizziness,dry mouth,insomnia,palpitations and other symptoms of points significantly lower than the control group(P〈0.05),but the tinnitus syndrome did not have statistically significant.Conclusion: The application of xu-zao-geng-ping-granule in the treatment of female climacteric hypertension,can boost the quality of life,and effectively improve the clinical symptoms.