中文摘要：

目的探讨泌尿系结石患者血脂及其他相关的影响因素。方法回顾性分析2010年4月—2011年5月我院就诊的214例泌尿系结石患者（尿石症组）及192例同期在我院健康体检正常者（对照组）健康体检时及患者入院后采集的外周血及尿液样本资料,检测血钙、磷、血尿酸、血脂、血浆脂蛋白、尿钙以及尿pH水平,比较两组各观察指标水平有无差异,并采用Logistic回归分析对泌尿系结石形成的危险因素进行统计分析。结果两组受检者血钙、血磷、二氧化碳结合力（CO2CP）、血尿酸水平比较,差异均有统计学意义（P〈0.05）;两组受检者血清三酰甘油（TG）、血浆脂蛋白E（ApoE）、高密度脂蛋白胆固醇（HDL-C）水平比较,差异均有统计学意义（P〈0.05）;而两组血清总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）、血浆ApoA、ApoB水平比较,差异均无统计学意义（P〉0.05）。Logistic回归分析结果进入模型的变量为高脂血症[OR=1.321,95%CI（1.145,1.467）],家族史[OR=2.234,95%CI（1.768,2.814）]。结论泌尿系结石患者与健康人血脂以及电解质水平存在差异,高脂血症及家族史是泌尿系结石形成的危险因素。

英文摘要：

Objective To explore the levels of blood lipids and related influencing factors in urolithiasis patients. Methods A total of 214 urolithiasis patients and 192 healthy subjects underwent physical examinations at our hospital between April 2010 and May 2011 were included in this study with their clinical data retrospectively analyzed.Blood and urine samples were taken either at the physical examination or after admission,with levels of blood calcium,blood phosphorous,blood uric acid,blood lipids,blood lipoproteins,urine calcium and pH of the urine compared between the two groups.Logistic regression analysis was applied to analyze the risk factors for the formation of urinary stones. Results Levels of blood Ca,P,CO2CP and uric acid were significantly different between the two groups（P〈0.05）;levels of serum TG,ApoE and HDL-C were significantly different between the two groups（P〈0.05）;levels of serum TC,LDL-C,ApoA and ApoB were not significantly different between the two groups（P〉0.05）.Multiple logistic regression analysis showed that hyperlipidemia and family history entered the variable model,with OR values and 95%CI of 1.321（1.145,1.467） and 2.234（1.768,2.814） respectively. Conclusion Differences exist in serum electrolyte and lipid levels between the urolithiasis and the healthy population.Hyperlipidemia is among the risk factors of urolithiasis pathogenesis.