中文摘要：

目的研究分析食管癌患者术后感染病原菌的耐药性,为治疗食管癌术后感染提供依据。方法选取2011年9月-2014年11月医院收治的235例食管癌术后感染患者,统计分析感染患者病原菌种类及其耐药性,采用SPSS18.0软件对数据进行统计分析。结果共分离出病原菌312株,其中革兰阴性菌254株占81.41%,革兰阳性菌37株占11.86%,真菌21株占6.73%;革兰阴性菌对头孢曲松、美洛西林、环丙沙星的耐药率较高,均〉50.00%,对亚胺培南的耐药率较低,〈33.00%;革兰阳性菌对苯唑西林、青霉素、阿奇霉素、头孢唑林及环丙沙星的耐药率较高,均〉50.00%,对万古霉素均较敏感,耐药率为0。结论食管癌患者术后感染的耐药菌以革兰阴性菌为主,临床应根据耐药菌的耐药性及特点,给予相应的治疗。

英文摘要：

OBJECTIVE To investigate the drug resistance of pathogens causing postoperative infections in the patients with esophageal cancer so as to provide guidance for treatment of the postoperative infections.METHODS A total of 235 esophageal cancer patients with postoperative infections who were treated in the hospital from Sep2011 to Nov 2014 were enrolled in the study.The species of drug-resistant pathogens causing the infections and the drug resistance were statistically analyzed,and the statistical analysis of data was performed by using SPSS18.0software.RESULTS Totally 312 strains of pathogens have been isolated,including 254（81.41%）strains of gramnegative bacteria,37（11.86%）strains of gram-positive bacteria,and 21（6.73%）strains of fungi.The drug resistance rates of the gram-negative bacteria to ceftriaxone,mezlocillin,and ciprofloxacin were more than 50.00%,and the drug resistance rate to imipenem was less than 33.00%.The drug resistance rates of the gram-positive bacteria to oxacillin,penicillin,azthromycin,cefazolin,and ciprofloxacin were more than 50.00%,and the drug resistance rate to vancomycin was 0.CONCLUSIONThe gram-negative bacteria are dominant among the drug-resistant pathogens causing the postoperative infections in the esophageal cancer patients.It is necessary for the hospital to conduct the appropriate treatment according to the drug resistance of the pathogens.