中文摘要：

通过滴涂和电聚合的方法制备了石墨烯（ GN）-多壁碳纳米管（ MWCNTs）/聚烟酸（ PNA）修饰玻碳电极。利用循环伏安法和差分脉冲伏安法考察了盐酸吡哆辛（ VB6）在此修饰电极上的电化学行为和测定方法。结果表明,VB6在此修饰电极上有一明显的不可逆氧化峰（Epa=1.049 V）,该电极与 GCE、PNA/GCE以及GN/MWCNT/GCE相比,VB6的氧化峰电流显著提高,电极反应为扩散控制的一电子两质子反应。利用差分脉冲伏安法对VB6进行测定,线性范围为0.05~200μmol/L,检出限为0.02μmol/L,相对平均偏差为3.1%（n=8）。本方法可用于测定VB6片和B族维生素片中的VB6含量测定,加标回收率为在96.1%~104.5%之间。

英文摘要：

Graphene （ GN） and multiwalled carbon nanotubes （ MWCNT） composites were coated on glassy carbon electrode （ GCE ） and then poly （ nicotinic acid ） （ PNA ） was electrodeposited on the modified electrode. The electrochemical behavior of pyridoxine hydrochloride （ VB6 ） was investigated at the modified electrode by cyclic voltammetry （ CV ） and differential pulse voltammetry （ DPV ） . Results showed the oxidation current of VB6 at the GN-MWCNT/PNA/GCE was obviously larger than that at GCE, PNA/GCE and GN/MWCNT/GCE. The oxidation process of VB6 was an irreversible diffusion-controlled process involving one electron and two protons. The liner range between the peak current intensity of DPV and the concentration of VB6 was 0 . 05-200 μmol/L with a detection limit of 0 . 02 μmol/L （ S/N=3 ） . The modified electrode showed a good reproducibility with a relative standard deviation of 3 . 1% （ n=8 ） . The proposed method was applied to the analysis of vitamin B6 in vitamin B6 tablets and compound vitamin B tablets with recoveries between 96 . 1%-104 . 5%.