中文摘要：

肾胺酶是新近发现的一种肾脏来源的单胺氧化酶与细胞因子,可降解儿茶酚胺以调节血压与心功能,并具有肾脏保护作用.肾胺酶的发现是肾脏与心血管领域研究的重要进展,有潜在的治疗应用价值.从肾胺酶的结构、功能、生理意义以及与疾病的关系等方面,回顾了相关研究进展,为进一步研究其功能与治疗应用奠定基础.

英文摘要：

Renalase,a newly-found monoamine oxidase and a cytokine from the kidney,can degrade circulatory catecholamines to regulate the cardiovascular and renal functions.In addition,it has renoprotective effects.Furthermore,it has potential therapeutic values in clinical practice.Herein,the progress on the study of the structure,function and significance of renalase in physiology and disease was reviewed,laying a solid foundation for to the further study.