中文摘要：

这研究的目的是调查显微镜的结构并且描绘大腿骨的头(ANFH ) 的 avascular 坏死的 cancellous 骨头。ANFH 的兔子模型被建立。组织病理学说的特征成功地被学习。类固醇注射组(S.G ) 和控制的组(C.G ) 之间的差别被检验，包括兔子， hematological 考试和三维的结构的重量。triglyceride (TG ) 什么时候在 S.G 增加了，被发现胆固醇(CHO ) 的血浆层次，高密度的脂蛋白(HDL ) 和在 S.G 的低密度的脂蛋白(LDL ) 是比在 C.G 的那些低的；但是骨头矿物质内容( BMC )和机关和织物的结构的模型索引( SMI )在大腿骨的头的 S.G 三维的结构显著地减少了用扫描的微计算断层摄影术( CT )被获得，机械模型被建立分析这些结构的变化的影响在上 cancellous 骨头的机械性质。大腿骨的头的关键词 Avascular 坏死 - Cancellous 骨头 - 微观结构 - 机械性质工程被中国(30470430 和 30400514 ) 的国家自然科学基础支持。

英文摘要：

The aim of this study is to investigate microscopic structure and characterize cancellous bone of avascular necrosis of the femoral head （ANFH）. The rabbit model of the ANFH is established. The histopathologic features are studied successfully. The differences between the steroidinjection group （S.G.） and the controlled group （C.G.） are examined, including the weight of rabbits, the hematological examination and the three-dimensional stnactures. It is found that the plasma levels of cholesterol （CHO）, high-density lipoprotein （HDL） and low-density lipoprotein （LDL） in S.G. are lower than those in C.G. when the triglyceride （TG） increased in the S.G.; but the bone mineral content （BMC） and the structural model index （SMI） of the organ and tissue decreased significantly in S.G. Three-dimensional structures of the femoral head are obtained using micro-computed tomography （CT） scanning and the mechanical model is established to analyze the influences of these structural changes on the mechanical properties of the cancellous bone.