中文摘要：

目的探讨太原市社区老年人轻度认知功能障碍的影响因素,为采取有效的预防措施提供科学依据。方法 2008年11月在太原市采用整群随机抽样方法选取9个社区的老年人群中轻度认知功能障碍者（MCI）232例,按年龄、性别、文化程度进行1∶1配对病例对照研究。用SPSS13.0软件进行单因素和多因素条件Logistic回归分析。结果单因素条件Logistic回归分析发现,职业、经济收入、身体状况、吸烟,血糖、舒张压、16PF中的因素A（乐群性）、因素F（兴奋性）、因素O（忧虑性）、因素Q2（独立性）、因素Q3（自律性）、高血压、糖尿病、冠心病、APOE-4在MCI组与对照组之间差异有统计学意义（P〈0.05）。多因素条件Logistic回归分析结果显示,经济收入、舒张压、16PF中因素F（兴奋性）、因素Q2（独立性）、因素Q3（自律性）、高血压、糖尿病、冠心病及APOE-4在MCI组与对照组之间差异有统计学意义（P〈0.05）,并且经济收入及16PF中的因素Q2、因素Q3是MCI的保护性因素[OR（95%CI）=0.481（0.258～0.894）,0.063（0.007～0.550）,0.072（0.013～0.560）],因素Q2（独立性）和因素Q3（自律性）存在交互作用,是轻度认知功能障碍的保护性因素（OR=0.710,95%CI：0.524～0.960）。结论舒张压、16PF中因素F（兴奋性）、高血压、糖尿病、冠心病及APOE-4是MCI的危险性因素。高经济收入、高独立性及高自律性为MCI的保护性因素,且高独立性并高自律性对MCI的影响分别存在主效应同时也存在联合作用效应。

英文摘要：

Objective To investigate the influential factors of mild cognitive impairment among the elders in community of Taiyuan City,in order to provide a scientific basis for effective preventive measures.Methods In November 2008,232 elders with mild cognitive impairment（MCI） were selected using cluster random sampling method in 9 communities of Taiyuan City,232 controls matched by age,sex and educational level were also recruited in this study.SPSS 13.0 software was used for univariate and multiple conditional Logistic regression analysis.Results Single-factor logistic regression analysis showed that the conditions,occupation,income,health status,smoking,blood glucose,diastolic blood pressure,16PF factors in A（warmth）,the factors F（liveliness）,factor O（aprehension）,factors Q2（self-reliance）,factor Q3（perfection）,hypertension,diabetes,coronary heart disease,APOE-4 in the MCI group and the control group was significantly different（P0.05）.Multivariate Logistic regression analysis showed that income, diastolic blood pressure,16PF factors in F（liveliness）,the factors Q2（selfreliance）,factor Q3（perfection）,hypertension,diabetes,coronary heart disease and APOE-4 in the MCI group and the control group was significantly different（P0.05）,and the economic income and the 16PF factors in Q2,factors that Q3 is an independent protective factors for MCI [OR（95% CI）=0.481（0.258～0.894）,0.063（0.007～0.550）,0.072（0.013～0.560）].With the factor Q2（self-reliance） and factor Q3（perfection） is a mild cognitive dysfunction protective factor（OR=0.710,95% CI：0.524～0.960）.Conclusions Diastolic blood pressure,16PF factors in F（liveliness）,hypertension,diabetes,coronary heart disease and APOE-4 are risk factors for MCI.High-income,high self-reliance and high perfection are protective factors for MCI.High self-reliance and high perfection have both principal effect and joint action-effect on MCI.