目的比较经肝动脉灌注化疗栓塞术(TACE)与单纯肝动脉灌注术(TAI)治疗胃癌肝转移瘤的疗效。方法回顾性分析50例胃癌肝转移患者的临床资料。结果 TACE组有效率和控制率[76%(19/25)和92%(23/25)]均明显较TAI组[28%(7/25)和68%(17/25)]高(P【0.05);TACE组0.5、1、2生存率[92%(23/25)、56%(14/25)、16%(4/25)]均明显较TAI组[64%(16/25)、40%(10/25)、8%(2/25)]高(P【0.05);两组不良反应发生率[36%(9/25)、28%(7/25)]比较差异不显著(P】0.05)。结论经肝动脉灌注化疗栓塞术较单纯肝动脉灌注术治疗胃癌肝转移瘤的疗效好。
Objective To compare the efficacy of hepatic transarterial chemoembolization and hepatic transcatheter arte-rial infusion alone in the treatment of gastric cancer liver metastases.Methods The clinical data of 50 cases of gastric cancer pa-tients with liver metastases were retrospectively analyzed.Results The effective rate and control rate of hepatic transarterial che-moembolization group were 76%(19/25) and 92%(23/25),which were significantly higher than those of hepatic transcatheter arterial infusion group 28%(7/25) and 68%(17/25) (P<0.05);the 6-month,1-,2-year survival rates of hepatic transarterial chemoembolization group were 92%(23/25),56%(14/25),16%(4/25),which were significantly higher than those of hepatic transcatheter arterial infusion group 64%(16/25),40%(10/25),8%(2/25) (P<0.05);the differences of incidence rates of adverse reactions between the 2 groups 36%(9/25),28%(7/25) were not significant (P >0.05).Conclusion Hepatic transarterial chemoembolization has better effects than hepatic transcatheter arterial infusion alone in the treatment of gastric canc-er liver metastases.