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A role for the ER stress sensor IRE1 in metabolic adaptation responses
  • 分类：TP212R333
  • 相关基金：support by the National Natural Science Foundation of China(Grant Nos.31230036 and 81021002)
关键词： branch, adaptation, PPAR, signaling, PROGRAMS, FASTING, MITOCHONDRIA, metabolism, MAMMALIAN, DEPRIVATION
中文摘要：

【正】Prof.Liu Yong’s laboratory at the Institute for Nutrition Sciences,Shanghai Institutes for Biological Sciences,Chinese Academy of Sciences,reported that the ER stress sensor IREl regulates fastinginduced metabolic adaptive programs through the XBPls-PPAR axis signaling in the liver,which was published in Nature Communications(2014,5:3528).The mammalian IRE1-XBP1 signaling branch of the cellular unfolded protein response plays a key role

英文摘要：

<正>Prof.Liu Yong’s laboratory at the Institute for Nutrition Sciences,Shanghai Institutes for Biological Sciences,Chinese Academy of Sciences,reported that the ER stress sensor IREl regulates fastinginduced metabolic adaptive programs through the XBPls-PPAR axis signaling in the liver,which was published in Nature Communications(2014,5:3528).The mammalian IRE1-XBP1 signaling branch of the cellular unfolded protein response plays a key role

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