目的:分析温下健脾法改善重度脓毒症患者胃肠功能障碍的临床效果。方法:连续选择90例重度脓毒症患者采用随机、双盲、对照方法将其分为三组,每组30例,即中西医治疗组(附桂姜黄汤配合常规西医治疗),对照1组(乳果糖配合常规西医治疗)和对照2组(常规西医治疗),对比治疗效果。结果:中西医治疗组的NRS2002和APACHEⅡ评分均较治疗前明显下降,显著低于其他两组(P〈0.05)。各组治疗前后的BMI、体重、中臂围和皮褶厚度的比较,差异均无统计学意义(P〉0.05)。治疗后各组的HGB、ALB、前白蛋白和转铁蛋白水平均较治疗前增加,且中西医治疗组改善的更明显(P〈0.05)。中西医治疗组的平均ICU时间和28d死亡率均显著低于其他两组(P〈0.05)。结论:温下健脾法可以改善重度脓毒症患者的胃肠功能障碍,有较大的临床应用价值。
Objective :To study the effect of warming spleen method improving gastrointestinal dysfunction in patients with severe sepsis .Method :A total of 90 consecutives were divided into three groups and each of 30 cases ,the combined group(Fugui Jianghuang decoction + common medical treatments ) ,compare one group (lactulose + common medical treatments)and compare two group (common medical treatments )by a random ,double-blind ,compare method ;then to compare effects differences .Results :The NRS2002 and APACHE Ⅱ scores in combined group were lower than be-fore treatment ,thus significantly lower than the other two groups (P〈 0 .05) . The BMI ,body weight ,middle arm circ-umference ,skin fold thickness values in the three groups were no statistical differences (P〉 0 .05) . The HGB ,ALB ,pre-albumin and transferring levels in the three groups were all higher than before ,what’s more ,they in combined group were significantly higher than the others(P〈 0 .05) . And the in-ICU days and mortality for 28 days in combined group were significantly less(P〈 0 .05) . Conclusion :Warming spleen method could furtherly improve gastrointestinal dysfunction in patients with severe sepsis .