中文摘要：

心形成从一个单个心试管开始，它从双边的初发的心领域熔化。发展中的心试管由外部层的心肌的房间和内部层的 endocardial 房间组成。precardiac 房间的几张不同人口贡献心脏的形态发生。然而，它在 gastrulation 舞台关于心内膜的系仍然保持不很清楚。从而，这研究集中了于在 cardiogenesis 期间在 gastrulation 和心内膜查明在 hypoblast 之间的关联。第一，熔化的心试管词法上接近导出内胚叶的咽地板，暗示那块咽地板可能被包进内胚叶的形成的可能性。第二， HNK1 在胚囊舞台强烈在 hypoblast 被表示并且随后出现在 cardiogenesis 的心内膜。而且，命运地图数据显示了标记 hypoblast 的那 DiI 也以后是在心内膜的现在。另一条证据是 hypoblast 移植，在 quail-hypoblast，衍生物能被 QCPN 抗体在 cardiogenesis 的心内膜识别的小鸡鹑怪物。简言之，我们的当前的数据建议在胚囊的内胚叶部分至少作出贡献到 cardiogenesis 的心内膜的形成。

英文摘要：

Heart formation commences from a single heart tube, which fuses from bilateral primordial heart fields. The developing heart tube is composed of outerlayer myocardial cells and innerlayer endocardial cells. Several distinct populations of precardiac cells contribute to cardiac morphogenesis. However, it still remains not very clear about the lineage of endocardium at gastrulation stage. Thereby, this study focused on ascertaining the correlation between the hypoblast in gastrulation and endocardium during cardiogenesis. Firstly, the fusing heart tube morphologically is closed to endoderm-derived pharynx floor, implying the possibility that pharynx floor might be wrapped into the formation of endoderm. Secondly, HNK1 is expressed in hypoblast strongly at gastrula stage and subsequently appeared in endocardium of cardiogenesis. Moreover, fate map data displayed that DiI labeled hypoblast was also present in endocardium later on. One more evidence is chickquail chimera of hypoblast transplantation, in which quailhypoblast derivative could be identified in endocardium of cardiogenesis by QCPN antibody. In sum, our current data suggests that endoderrn in gastrula contribute at least partly to the formation of endocardium of cardiogenesis.