目的:了解和证实鼻内镜下聚焦超声治疗变应性鼻炎(AR)的临床效果。方法:采用鼻内镜下CZB型聚焦超声治疗仪对持续性中-重度AR患者60例进行超声手术治疗,手术部位以下鼻甲表面和鼻中隔前上部为主,观察并记录术后7 d、1个月、6个月患者临床症状和体征的变化,并于术后1、2、3年进行定期随访,以数字评分法判定疗效。结果:术后7 d、1个月、6个月评分与术前比较差异均有统计学意义;术后1、2、3年评分与术前比较差异均无统计学意义。随着随访时间的延长,失效患者逐渐增多,但均未发生任何手术并发症。结论:鼻内镜下聚焦超声治疗AR具有较高的临床安全性,短期疗效显著,但如何提高其远期效果有待进一步研究。
Objective: To analyze the efficacy of therapy for allergic rhinitis(AR) with focused ultrasound under endoscopy.Methods: Sixty patients were performed by focused ultrasound therapy.All cases were followed up in outpatient on day 7,1 month,6 months after operation, as well as 1 year,2 years and 3 years afterwards.The efficacy was recorded and analyzed according to the Chinese Lanzhou principle of treatment and recommendation program for allergic rhinitis(2004). Results: There was statistical significance difference between scores of 7 days,1 month,6 months after operation,but no significant difference since 1 year later.And the total effective rate reduced along with the extension of time.Conclusion: A good short-term curative effect of the focused ultrasound operation under endoscopy treating AR is available,however,its long-term efficacy should be improved.