中文摘要：

整体柱具有通透性能良好和传质速度快等特点，可实现快速、高效、高通量的分离，近年来已引起人们的热切关注。聚合物整体柱是其中应用最为广泛的一种，它是由单体、交联剂、致孔剂和引发剂等通过原位聚合得到的连续均一的棒状聚合物，具有取材广泛，使用pH范围比较宽，生物兼容性好等特点，通过化学修饰，可以用作多种色谱模式的固定相。该文主要综述了2003年至2006年期间有关聚合物整体柱制备和应用的研究进展。

英文摘要：

In the past years, comprehensive attention has been paid on the monolithic materials for high performance liquid chromatography （HPLC） and capillary electrochromatography （ CEC）, due to their superior porosity, good permeability, large surface area and high diffusion mass transfer. They are well suited for both small molecules and large biopolymers. Monolithic polymer based stationary phases are the continuous unitary porous structure prepared by in situ polymerization inside the column tube and, if necessary, the surface can be functionalized with various functional groups. This review summarizes the development in preparation and application of polymer monoliths, mainly according to the literature published from 2003 to 2005.