中文摘要：

[目的]探讨重症肌无力（MG）患者血清中乙酰胆碱受体抗体（AchRAb）以及肌肉特异性激酶抗体（MuSKAb）与临床特点的关系．[方法]应用酶联免疫吸附试验（ELISA），对40例MG患者血浆进行AchRAb和MuSKAb检测，并与患者临床特点进行比较分析．[结果]40例MG患者中AchRAb阳性为13例（33％），MuSKAb阳性为7例（18％），AchRAb与MuSKAb双阴性为22例（55％），AchRAb与MuSKAb双阳性为2例（5％）．[结论]MG患者中AchRAb阳性者的病情普遍较轻，可受胸腺影响；MuSKAb阳性患者女性多见，全身症状严重．

英文摘要：

OBJECTIVE To investigate the relationship of acetylcholine receptor antibody （AchRAb） and muscle specific kinase antibodies （MuSKAb） in the serum of myasthenia gravis （MG） and their clinical characters. METHODS The AchRAb and MuSKAb in the serum of 40 patients with MG were detected by ELISA, and were comparatively analyzed with their clinical characters. RESULTS Out of 40 patients with MG, the AchRAb was positive in 13 case （33%）, MuSKAb was positive in 7 case （18%）, both AchRAb and MuSKAb were negative in 22 cases （55%）, and were positive in 2 cases （5%）. CONCLUSION The patients with MG with AchRAb positive have mild clinical symptoms affected easily by thymus symptoms, and with MuSKAb positive are more in female patients with serious clinical symptoms.