目的研究黄荆Vetix negundo Linn.的酚类成分。方法黄荆70%乙醇提取物的乙酸乙酯部位采用硅胶、Sephadex LH-20、ODS柱进行分离纯化,通过波谱数据鉴定所得化合物的结构。结果从中分离得到7个化合物,分别鉴定为木犀草素4'-O-β-D-吡喃葡萄糖苷(1)、isoorientin6"-O-caffeate(2)、3,4,5-三咖啡酰奎宁酸(3)、右旋松脂酚酸-4-O-β-D-葡萄糖苷(4)、4-甲氧基-迷迭香酸甲酯(5)、苄基7-O-β-D-葡萄糖苷(6)、丹参素甲酯(7)。结论所有化合物均为首次从该植物中分得,化合物1、3、5-7为首次从牡荆属植物中分得。
AIM To study the phenols from Vitex negundo Linn.. METHODS The ethyl acetate fraction of 70% ethanol extract from V. negundo was isolated and purified by silica, Sephadex LH-20 and ODS column, then the structures of obtained compounds were identified by spectral data. RESULTS Seven compounds were isolated and identified as luteolin-4'-O-β-D-glucopyranoside (1), isoorientin 6"-O-caffeate (2), 3, 4, 5-tricaffeoyl quinic acid ( 3 ), ( + ) -pinoresinol-4-O-β-D-glucoside ( 4 ), methyl isoferuloyl-7- ( 3, 4-dihydroxyphenyl ) lactate (5), benzyl 7-O-β-D-glucoside (6) and oresbiusin A (7). CONCLUSION All the compounds are isolated from this plant for the first time, and compounds 1, 3, 5 -7 are first isolated from genus Vitex.