双眼视差在立体视觉中发挥着重要的作用,然而到目前为止双眼视差引起的立体视觉如何激活大脑皮层仍没有得出一致结论,需进一步研究.因此设计了一组功能核磁共振(functional Magnetic Resonence Imaging,fMRI)实验来定位与立体视觉有关的大脑皮层,实验中使用改进的随机点立体图(Random D Stereogram,RDS)作为视觉刺激,采用块状实验设计并使用SPM8分析数据.结果如下:1)hV3A(V3辅助区上侧),LG(舌回)hMT/V5(第5视区上侧)LOS(枕外侧沟)以及VIPS(腹侧顶内沟)是主要激活区.2)背侧视觉通路激活强烈而腹侧视觉通路激活较少.由此推论:1)没有一个单独的区域或皮层可以完全解释立体视觉感知,立体视觉的形成是不同区域通力合作的结果.2)背侧视觉通路在处理立体视觉中发挥着重要的作用.实验中得到的激活区域与其他实验结果有些差异这里主要讨论大脑激活区域以及产生差异的原因,通过分析比较这些结果,立体视觉的机制可以得到进一步的理解.如果可以明确立体视觉正常者的激活区域,那么利用fMRI扫描来筛查弱视会更简单有效.
Binocular disparity is of vital importance in stereoscopic vision. How binocular disparity activates brain regions has not been conclusively elaborated. An fMRI (functional magnetic resonance imaging) experiment was designed to locate cortex areas related to stereoscopic vision using modified random dot stereogram (RDS) as stimuli. Adopted block design was used and SPM8 was used to analyze data. It has been found that hV3A, LG, hMT/VS, LOS and VIPS were the main activated regions. The dorsal stream areas were strongly activated while ventral stream areas were only slightly activated. Therefore(here was no single region that could account for stereoscopic depth perception completely. Stereoscopic vision was probably produced by several regions together. (he dorsal stream system played an important role in processing stereoscopic vision. Some differences were found between the activating areas and results from previous experiments, and these were discussed. A comparison was made with other studies, to further understand mechanisms of binocular disparity. If activation areas among people with normal stereoscopic vision could be made clear and definitive, it would contribute to screening amblyopia more easily and efficiently by using fMRI scanning.