目的:了解中医治疗多发性硬化的疗效及疗效评价方法运用现状,为构建中医治疗多发性硬化的疗效评价体系提供借鉴。方法:检索1985—2010年国内中文期刊发表的中医治疗多发性硬化的临床随机对照或对照试验文献,将疗效评价相关的信息录入数据库,并对资料进行汇总分析。结果:共检索到符合标准的中医治疗多发性硬化文献9篇,文献采用的诊断标准、疗效评价标准、疗效评价指标较为混乱,不同文献的观察疗程相差悬殊;疗效评价结果提示,中医治疗多发性硬化的总体有效率、对神经症状体征的改善以及对减少复发次数上均优于对照组。结论:现有文献报道的中医治疗多发性硬化的疗效表现形式复杂多样,疗效评价方法混乱,应根据中医的疗效特点构建疗效评价体系,以使中医治疗多发性硬化的疗效得到医药界同行的认同。
Objective:To review the curative effect of traditional Chinese medicine(TCM)to Multiple Sclerosis(MS)and the evaluation.methods,in order to offering reference for the construction of evaluation system about MS treated by TCM.Method:Search the clinical literature of MS treated by TCM which published in the domestic Chinese journals from 1985 to 2010,input the information of curative effect into database,and study the data.Result:9 literature of MS treated by TCM which meet the criterion are retrieved.Diagnostic criteria,curative effect evaluation criteria,and indicators of curative effect of literature are chaos.Course of treatment is disparity between the difference literature;evaluation results suggest that the TCM treatment of MS are better than the control group on the overall effect,the improvement of neural symptoms and physical sign and the decrease of recurrence time.Conclusion:Manifestations of curative effect are complex and varied,evaluation methods of curative effect are confusion,the existing literature reported about MS treated by TCM.The evaluation system of curative effect should be constructed based on the characteristics of traditional Chinese medicine,so that the curative effect of Chinese medicine treatment of MS will be recognized by the medical sector counterparts.