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对苯基苄基醚类化合物的合成
  • 分类:TQ457.25[化学工程—农药化工]
  • 作者机构:浙江工业大学化学工程学院,浙江杭州310014
  • 相关基金:国家自然科学基金资助项目(21376224)
中文摘要:

以醇类化合物为原料,对苯基溴苄为羟基保护基试剂,Na H为碱,DMF为溶剂,在N2保护下反应,制备一系列的对苯基苄基醚类化合物,收率良好。

英文摘要:

A facile and efficient protocol for the protection of hydroxyl groups with p-phenylbenzyl(PPB) group has been studied. The reaction was performed with p-phenylbenzyl bromide as the hydroxyl protection agent and Na H as the base in the solvent of DMF under N2 atmosphere. A variety of alcohols can be protected to their corresponding PPB ethers in high yields.

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