中文摘要：

药物核磁共振定量分析法,操作简便,样品用量少,定性鉴定和定量分析同步完成,无须被测物的标准对照品,只须一般内标即可完成定量分析,分析速度和精密度可以达到或接近HPLC法.作为药物的水溶性维生素,中国药典中还没有核磁共振定量分析方法.实验数据表明,用核磁共振定量分析法与中国药典中提供的水溶性维生素分析法的分析结果十分吻合,可以达到药品市场监管的要求.

英文摘要：

NMR quantitative analysis of drug is the method with simple operation and use just a few amount of samples.The method can accomplish the qualitative as well as the quantitative analysis simultaneously,and do not need any standard compound but only the common internal standard for the quantitative analysis.The analysis speed and the precision of the method is close to the HPLC method.In this paper,the results of determination for water-soluble vitamin by NMR quantitative analysis with chemical analysis have been compared.The experiment shows the results of the NMR quantitative analysis are coincident with the result of the chemical method.Therefore,the NMR quantitative analysis method can be used market regulation of drugs.