中文摘要：

以间苯二酚、甲醛为原料制备间苯二酚-甲醛树脂微球,探讨碳酸钠、预聚合温度、表面活性剂浓度以及搅拌速度对微球尺寸的影响。以自制的羟基磷灰石粉末为原料,间苯二酚-甲醛树脂微球混合莰烯为致孔剂来制备具有多孔连通性结构的羟基磷灰石微球。结果表明：利用此种混合型致孔剂,既能使羟基磷灰石微球获得连通性孔结构,也能使其具有和间苯二酚-甲醛树脂微球尺寸类似的大孔洞。这种具备合适大孔且相互连通孔结构的羟基磷灰石微球在组织工程领域具有潜在的应用前景,其方法也为多孔材料的制备及结构优化提供了新的思路。

英文摘要：

Resorcinol-formaldehyde resin microspheres are prepared by using resorcinol and formaldehyde as raw materials.The effects of sodium carbonate,pre-polymerization temperature,surfactant concentration,and stirring speed on the size of microspheres are investigated.The obtained RF resin microspheres together with camphene are used as pore-foaming agent to fabricate porous hydroxyapatite microspheres by taking hydroxyapatite as raw material.Results show that the mixed pore-foaming agent can make hydroxyapatite microspheres gain connective pore structure and own large pores with the size similar to resorcinol-formaldehyde resin microspheres.Such hydroxyapatite microspheres have potential application prospect in tissue engineering field.The method also offers new ideas for preparing porous materials and structure optimization.