中文摘要：

以聚乙二醇单甲醚（MPEG）为原料,采用先磷酰化再水解的方法合成了聚乙二醇单甲醚磷酸酯（P-MPEG）.以P-MPEG为空间位阻剂,采用共沉淀法合成了内核为纳米羟基磷灰石（nHA）、壳层为MPEG链的纳米杂化材料.用傅里叶变换红外光谱（FTIR）、X射线衍射（XRD）、透射电子显微镜（TEM）和激光粒度分析（LPSA）对材料结构进行了表征.结果表明,所合成的杂化材料不仅能在水中再分散,而且可以在甲醇和二甲基甲酰胺（DMF）等有机溶剂中再分散.

英文摘要：

Poly（ethylene glycol ether） phosphate（P-MPEG） was synthesized through phosphorylating and hydrolyzing using poly（ethylene glycol methyl ether）（MPEG） as raw material.Then hybrid material with nHA core and polymer shell was synthesized through precipitation with P-MPEG as the steric hindrance agent.The nHA was characterized by Fourier transform infrared spectroscopy（FTIR）,X-ray diffraction（XRD）,transmission electron microscopy（TEM） and laser particle size analyzer（LPSA）.The synthesized hybrid material is redispersible not only in water,but also in organic solvents such as methanol,N,N-dimethylformamide（DMF）,etc.Feasibility of nHA with excellent redispersible ability using organic phosphate as the steric hindrance agent was confirmed.