目的 了解肾盂癌合并输尿管癌的临床特点. 方法 对四川大学华西医院2002至2012年收治的28例肾盂癌合并输尿管癌患者的临床资料进行回顾性研究分析. 结果 本研究纳入男性患者19例,女性患者9例,平均发病年龄66. 9岁. 血尿及腰部症状为最常见症状. 28例患者全部行输尿管癌根治术. 术后病理诊断均为尿路上皮癌,部分患者伴有鳞癌及腺癌. 28例均获得随访,随访时间为1~31月,平均19月. 术后总2年生存率33. 3%,Tis、Ta、T1、T2期50%,T3为23%,T4期0%;低级别尿路上皮癌50%,高级别尿路上皮癌33. 3%. 结论 肾盂癌合并输尿管癌患者具有更高的病理分期和分级,且预后更差,早期发现、早期诊断和治疗是提高远期生存率的重要因素.
Objective To investigate the clinical characteristics of renal pelvic carcinoma associated with ureteral carci-noma patients who underwent surgical therapy in the West China Hospital of Sichuan University. Methods Retrospectively ana-lyze the data of 28 cases were proved with renal pelvic carcinoma associated with ureteral carcinoma by pathology. Results The study included 19 male and 9 female patients. The average age of morbidity was 66. 9 years old. All the 28 cases underwent nephroureterectomy. The pathology diagnosis were confirmed with urological epithelial carcinoma and some patients were associated with adenocarcinoma or squamous cell carcinoma. All the 28 cases were followed up from 1-31months. The 2 year survival rates of Tis、Ta、T1、T2 was 50%,of T3 was 23%,of T4 was 0%. Conclusion Renal pelvic carcinoma associated with ureteral carcinoma have a very poor prognosis. The early diagnosis,treatment are the key points for the prognosis of patients with this rare kind of dis-ease.