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中文摘要：
传统的电化学DNA生物传感技术通常包括以下3个步骤，即电极表面探针DNA的固定、固液两相间DNA的杂交反应和电化学信号的读出，由于探针和目标序列的杂交过程发生在两相间，所以降低了杂交效率。在此，我们基于主客体识别和分子信标技术，设计了一种新型的电化学DNA传感器，可实现DNA在均一水相中的杂交反应，然后杂交体被捕获到电极表面进行电化学检测，具有高的灵敏度和选择性。
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