中文摘要：

羟基磷灰石（Hydroxyapatite，HAP）具有与人体骨骼和牙齿的无机成分相类似的结构，从而显示出高度的生物相容性和成骨细胞诱导性，广泛应用于骨的替代材料和填充材料以及多肽和蛋白质的分离．近年来，有关羟基磷灰石作为药物载体的研究日益增多，但很多研究都以烧结的HAP作为药物载体，而这种HAP因结晶度较高很难降解和吸收，从而影响了药物的释放速度．溶菌酶（Lysozyme，LZ）是一种由129个氨基酸构成的一条多肽链状粘多糖溶解酶，能破坏细菌胞壁从而杀死细菌，具有抗菌、抗病毒并加快组织恢复等作用．

英文摘要：

Nano-composite of hydroxyapatite/lysozyme with a size of 100 nm was synthesized in situ by chemical wet method, and characterized by nitrongen gas adsorption method, IR, SEM and UV-Vis spectroscopic techniques. In comparison with that synthesized by the dipping adsorbing method, the composite synthesized by wet method has much more content and activity of lysozyme. These results suggest the composite can be used as a controlling carrier of releasing lysozyme.