中文摘要：

阿尔茨海默病的发病原因及发病机制至今尚未明确，本文总结近1年来阿尔茨海默病转化医学研究的突破性进展，从阿尔茨海默病的病因、发病机制、检测方法及靶向治疗等方面作一简要综述。

英文摘要：

Nowadays,the exact causes and pathogenesis of Alzheimer＇s disease are still un- clear. This article summarized the breakthrough advances of Alzheimer＇s disease applied research in this year,including the causes and pathogenesis of Alzheimer＇s disease, early detection method and target therapy.