LIU Jun-Wei:Ph.D. candidate in the Department of Electronic Science and Technology, University of Science and Technology of China (USTC). He received his bachelor degree from USTC in 2004. His research interest covers image processing and analysis, level set, pattern recognition, and video compression. Corresponding author of this paper. E-mail: jwliu4@mail.ustc.edu.cn FENG Huan-Qing:Professor at the Institute of Biomedical Engineering (BME), University of Science and Technology of China (USTC). He graduated from USTC in 1970. From 1981 to 1983, he visited Uni- versity of Wisconsin-Madison as a visiting scholar in the Center of BME. From 1991 to 1993, he worked as a research associate in the Department of BME, Case Western Reserve University. His research interest covers bioinformatics, medical imaging,biomedical signal processing, and computer-based medical instrumentation. E-mail: hqfeng@ustc.edu.cn ZHOU Ying-Yue:Master student in the Department of Electronic Science and Technology, University of Science and Technology of China. Her research interest covers medical image processing and image registration. E-mail: zyyzhou@inail.ustc.edu.cn LI Chuan-Fu:Postdoctor in the Department of Electronic Science and Technology, University of Science and Technology of China, and chief physician at the Medical Image Center, the First Affiliated Hospital, Anhui College of Traditional Chinese Medicine. His main research interest is medical imaging. E-mail: licf@mail.ustc.edu.cn