中文摘要：

目的：探索肠癌患者是否存在某些穴位的痛觉敏化及穴位痛敏面积扩大现象。方法：共纳入30例肠癌患者与30例健康受试者,采用电子Von Fray检测仪测定与胃肠疾病相关的13个穴位及其周围1寸、2寸和该穴位相应的同神经节段的参照点的压痛阈值,并与该穴位异神经节段的参照点压痛阈值比较计算痛阈的相对值,和健康受试者的相对压痛阈值比较,分析肠癌患者体表相关穴位压痛阈的变化。结果：在足三里、上巨虚、下巨虚、曲池、大肠俞,肠癌患者的压痛阈值较健康受试者均显著下降（P〈0.05,P〈0.01,P〈0.001）,在这些穴位旁开1寸和2寸及其同神经节段非穴位点,其压痛阈值也较对照组均显著下降（P〈0.05,P〈0.01,P〈0.001）。而阴陵泉穴的敏化区域集中在穴位及其旁开1寸,其同神经节段非穴位点也出现敏化（P〈0.01,P〈0.001）。结论：肠癌患者在足三里、上巨虚、下巨虚、曲池、大肠俞及阴陵泉穴出现穴位压敏和面积扩大现象。

英文摘要：

Objective To judge whether algesia sensitization of some acupoints is existed and whether the acupoint algesia sensitization area is expanded in the patients of intestinal cancer.Methods Totally, 30 patients of intestinal cancer and 30 healthy subjects were included. The electronic Von Fray was used to determine the pressure-pain thresholds at 13 acupoints relevant with gastrointestinal disorders and the reference points at the sites 1cun and 2cun lateral to those points as well as the sites at the corresponding nerve segments. Compared with the pressure-pain thresholds at the reference points of the different segments, the relative value was calculated. The changes were analyzed in the pressure-pain thresholds at the relevant acupoints on the body surface in the patients of intestinal cancer as compared with the relative pressure-pain thresholds in the healthy volunteers.Results The pressure-pain thresholds at Zusanli （ST 36）, Shangjuxu （ST 37）, Xiajuxu （ST 39）, Quchi （LI 11） and Dachangshu （BL 25） in the patients of intestinal cancer were all significantly reduced as compared with those of the healthy subjects （P〈0.05,P〈0.01, P〈0.001）. At the non-acupoint sites 1 cunand 2 cun lateral to those acupoints as well as at the sites of the same segments, the pressure-pain thresholds were reduced significantly as compared with the control group （P〈0.05,P〈0.01, P〈0.001）. Particularly, the sensitization zone of Yinlingquan （SP 9） focused on the acupoint, the site 1cun lateral to it as well as the non-acupoint sites of the same segments （P〈0.01, P〈0.001）. Conclusion The acupoint sensitization is displayed at Zusanli （ST 36）, Shangjuxu （ST 37）, Xiajuxu （ST 39）, Quchi （LI 11）, Dachangshu （BL 25） and Yinlingquan （SP 9） and the sensitization area is expended in the patients of intestinal cancer.