本文介绍一种新颖、灵活的微胶囊制备方法——乳滴模板法。胶体粒子在乳滴表面自组装形成有序的球面胶体壳,交联固定乳滴表面的胶体粒子制备新型的“胶体体(colloidosome)”微胶囊,即以胶体粒子为壳的微胶囊。乳滴模板法制备微胶囊的优点是方法简单,胶囊的尺寸、渗透性、机械强度容易调控。这种新型的微胶囊在功能食品、药物载体、生物医药,尤其是细胞移植等领域具有潜在的应用前景。
The present article focuses on a facile and versatile technique of emulsion droplet template method, developed for preparing novel microcapsules. Colloid particles adsorb on the surface of the emulsion droplets and selfassemble into an ordering spherical solid shell. Cross-linking and fixing the shell, the novel capsule "colloidosome", which is composed of a close-packed shell of colloid particles, can be fabricated. The strategy outlined readily affords the facility of fabrication and precise control over the size, permeability, mechanical strength of the capsules. Consequently these capsules have potential applications in functional foods, drug delivery, biomedicine, especially cell transplant.