中文摘要：

目的：研究野八角果实的化学成分及生物活性。方法：应用硅胶、反相及半制备HPLC色谱法对野八角果实的乙醇提取物进行分离纯化，并用MTT法对所分离化合物进行细胞毒活性测试。结果：分离鉴定了8个化合物，包括1个新的苯丙素糖苷2，4-dihydroxy—allylbenzene-2-O-β-D—glucopyranoside（1）和7个已知的倍半萜内酯oligandruminB（2），oligandruminD（3），anisatin（4），veranisatinD（5），pseudomajucin（6），la—hydroxy-3-deoxy—pseudoanisatin（7），8a—hydroxy-10-deoxycyclomerrillianolide（8）。结论：化合物1，2，3，5-8为首次从野八角果实中分离得到，所有化合物对非小细胞肺癌A549细胞株均无细胞毒活性。

英文摘要：

AIM： To study the constituents and bioactivity of lllicium simonsii. METHODS： The extracts of the fruits of lllicium simonsii were submitted to a combination of chromatographic materials, silica gel, ODS column chromatography and finally preparative HPLC to obtain eight compounds which were further evaluated for their cytotoxicity by MTT method. RESULTS： A new phenylpropanoid glycolside, 2, 4-dihydroxy-allylbenzene-2-O-fl-D-glucopyranoside （1）, together with seven characteristic sesquiterpene lactones, oligandrumin B （2）, oligandrumin D （3）, anisatin （4）, veranisatin D （5）, pseudomajucin （6）, la-hydroxy-3-deoxy-pseudoanisatin （7）, 8a-hydroxy-10-deoxycyclomerrillianolide （8） were isolated. CONCLUSION： Compound 1 is new. Compounds 1, 2, 3, 5--8 were isolated from this plant for the first time. None of the isolates showed inhibitory effects on the growth of non-small cell lung tumor cell line A549.