中文摘要：

阐述纳米颗粒在血脑屏障相关的脑部疾病研究中的进展,分析应用在血脑屏障研究中的几类纳米颗粒,分别对治疗、诊断/追踪及多功能纳米颗粒的材料组成、功能特点和应用现状进行评述.介绍在靶向纳米颗粒穿透血脑屏障可视化研究中的成果,指出纳米颗粒在血脑屏障研究中的发展方向.

英文摘要：

Recently,the advancements in nanotechnology and better understanding of the BBB physiology have promoted the use of nanoparticles for targeted delivery across the BBB for therapy of neuronal diseases/disorders.This review summarizes the applications of several classes of novel nanoparticles to blood-brain barrier(BBB)for therapy,diagnosis,dynamic imaging,and multifunctional mode,including the materials,functions characteristics,as well as their current research status.Our recent progress on visualization of...