中文摘要：

近十余年来,我国原发性开角型青光眼（以下简称开青）患病率逐年上升,由0.29%上升到2.6%,一跃成为最重要的不可逆性致盲眼病。由于对开青眼压升高及视神经损害的机制认识不清,缺乏可行的筛查及有效的干预技术,其致盲率远高于发达国家8%的平均水平。王宁利教授所领导的项目组从回答开青眼压升高和视神经损害的关键科学问题入手,以解决开青筛查和监测的关键技术和设备为突破口,在阐明开青发病机制的基础上建立了基于机制的新分类体系,并在新理论、新分类基础上创建了新的开青筛查、诊断、监测和治疗技术,在全国范围内推广应用。覆盖人群1.2亿,实际受益患者320万人,减少因开青致盲约32万人,开青致盲率由15%下降到5%,减少开青致残约64万人,致残率由30%下降到15%。

英文摘要：

In the recent 10 years,the prevalence of primary open angle glaucoma（ POAG） in China has been increased from 0. 29%to 2. 6%,and POAG becomes the most important irreversible blindness disease. As it is still in vague of the mechanism of intraocular pressure elevation and impairment of optic nerve,and lacks of screening and prevention technology,the blindness rate of POAG is higher than 8% w hich is the average level of developed country. Leading by Professor Ningli Wang,this program established the new POAG prevention and treatment system by resolving the mechanism of POAG and the key technology and instrument. The new technology and instrument has been applied in over 26 provinces and over 300 districts,w hich covered 120 million peoples. There are3. 2 million patients have been benefited from this program. The blindness rate of POAG has reduced from 15% to 5%,and the disable rate reduced from 30% to 15%.