中文摘要：

dinitratobis (phen ) 的 DNA 有约束力的性质镉建筑群[Cd (phen ) 2 (NO3 ) 2 ]( 在哪儿 phen1,10-phenanthroline ) 与吸收滴定，荧光光谱学，粘性测量，分子的建模和密度被调查了功能的理论(DFT ) 计算。是弱沟绑定而非部分 intercalative 相互作用的建筑群的 DNA 有约束力的模式扩大平面芳香的 phen 戒指期望的结果 indictate。另外， DNA 劈开学习被胶化电气泳动实验执行。结果证明建筑群几乎两个都不在缺席和现在的 ascorbate 劈开 pBR322 DNA。镉建筑群的形成能减少，这因此被建议镉毒性到一些程度。

英文摘要：

DNA-binding properties of the dinitratobis（phen） cadmium complex [Cd（phen）2（NO3）2] （where phen = 1,10-phenanthroline） have been investigated with absorption titration, fluorescence spectroscopy, viscosity measurement, molecular modeling and density functional theory （DFT） calculations. The results indictate DNA-binding mode of the complex to be weak groove binding rather than partial intercalative interaction expected of the extended planar aromatic phen ring. In addition, the DNA cleavage study was carried out by gel electrophoresis experiment. The results showed that the complex both hardly cleaves pBR322 DNA in the absence and present ascorbate. So it is suggested that the formation of cadmium complex can decrease cadmium toxicity to some extents.