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临床微生物实验室自动化现状与进展
  • 期刊名称:中华临床实验室管理电子杂志
  • 时间:2014.5.1
  • 页码:4-10
  • 分类:R446.6[医药卫生—诊断学;医药卫生—临床医学]
  • 作者机构:[1]中国医学科学院北京协和医学院北京协和医院检验科,100730
  • 相关基金:国家自然科学基金资助项目(H1908,81101287)
  • 相关项目:中国碳青霉烯不敏感大肠埃希菌和肺炎克雷伯菌的流行病学和耐药机制
中文摘要:

随着微生物检验技术的发展,特别是基质辅助激光解析电离一飞行时间质谱技术以及微生物标本液体转运技术的运用,使微生物实验室自动化愈加可行。人们期盼的成功的自动化系统设计灵活,能将实验室人员从一些技术要求较低的、能由仪器完成的工作中解脱出来,从而提高标本处理效率,并减少资源浪费。目前,研发和使用的微生物实验室自动化系统可分为三大部分,第一部分为标本处理系统,第二部分为能提供全微生物实验室自动化解决方案的系统,包括为达到不同级别自动化程度的各种模块,第三部分为各种微生物自动化鉴定和药敏系统。现在,临床微生物检验流程已进入革新时代,虽然大量的评估工作还有待完成,但微生物自动化系统必将对临床微生物实验室工作水平的提高与技术发展产生深远的影响。

英文摘要:

The automation of clinical microbiology laboratory has become more and more available with the development of technology of clinical microbiology, especially the application of the matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) and liquid-based microbiology specimen transport system. A successful automation system requires flexibility in the design, which can liberate the personnel of laboratory from some tasks that can be done by the inslruments, thereby improving the efficiency of specimen process and reducing the waste of resources. Currently, there are three parts of automation system applied in the clinical microbiology laboratory. The first one is the specimen processor system. The second one is the solution system offering full microbiology laboratory automation, including various modules for attaining diverse automation degree. The third one is the automatic bacteria identification/antimicrobial susceptibility testing system. Nowadays, the detection process of clinical microbiology has entered the era of innovation. Although a lot of assessment works remains to be done, the microbe automatic system will have a profound impact on improving the work standard and technology of clinical microbiology laboratories.

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