目的评价青少年慢性心理社会应激暴露对BMI变化的影响。方法2011年9月在江苏省徐州市区10所中学对初一和高一年级学生进行体格检查和问卷调查,收集社会人口学特征、青春期发育等级、父母肥胖程度和心理社会应激程度等信息,采用青少年多维生活事件多维评定问卷的编制和信效度检验(MLERQ)作为心理社会应激暴露测定,该量表包括家庭生活事件、学校生活事件、同伴关系、两性关系及健康成长5个维度,利用多元线性回归分析基线应激对随访BMI变化的影响,使用交互分析检验基线BMI和应激对BMI改变的交互作用。结果基线调查共获得5473(男性2841,女性2632)名中学生完整数据。2013年9月获取第二轮体格检查数据,队列研究共获得4316(男性2171,女性2145)名学生完整数据,失访1157人。随访研究表明基线超重/肥胖的女l生青少年基线应激总分和随访BMI—Z分增加呈正相关,且相关性在控制了年龄、青春发育等级、父母亲肥胖程度和社会经济状况等协变量后,差异仍具有统计学意义(P〈0.01),男性无论在体重正常或超重朋巴胖组,基线应激总分和随访BMI—Z分变化相关性的差异无统计学意义。结论慢性心理社会应激暴露可导致青春期超重/肥胖女性BMI增加。提示女性超重朋巴胖青少年为慢性心理社会应激致体重增加的易感人群。
Objective To evaluate the influence of chronic psychosocial stress on BMI in adolescents. Methods Physical examination and questionnaire survey were conducted among the students of junior grade 1 and senior grade 1 in 10 middle schools in Xuzhou in September 2011. Their body height and weight were measured at baseline survey and the self-report information about socio-demographic data, emotional symptoms (depressive symptoms, anxiety symptoms), and life style/behavior were collected from them. Chronic psychosocial stress was assessed with Multidimensional Life Events Rating Questionnaire (MLERQ), which consists of five items, stress of family life, school life, peer relation, gender relation and health growth. Results A total of 5 473 valid questionnaires were collected for analysis (2 841 from boys and 2 632 from girls). The follow-up measurement of body height and weight were conducted in September 2013. A total of 4 316 students (2 171 boys, 2 145 girls) were surveyed, and 1 157 students missed the follow up. The psychosocial stress score in the overweight and obese girls at baseline survey was positively associated with BMI-Z increase at follow up survey (P〈0.01). No such effect was observed among the boys at follow-up survey. Conclusion High level of chronic psychosocial stress could lead to BMI increase in overweight and obese girls, suggesting that female adolescents are susceptible population of psychosocial stress induced obesity.