量子点作为一种新型荧光标记物,与有机染料和荧光蛋白质相比,它们具有可调谐且宽的吸收光谱,激发可产生多重荧光颜色、强荧光信号、抗光漂白能力强等独特的光学特性,使其广泛应用在生物和医学领域。该文就量子点探针的表面修饰和功能化及其标记技术的研究进展进行了阐述。
As emerging promising fluorescent labels,semiconductor quantum dots (QDs) have tremendous potential in the fields of biology and medicine because of their unique optical properties with size-tunable light emission,broad absorption spectra for simultaneous excitation of multiple fluorescence colors,superior signal brightness,resistance against photobleaching,etc. This article briefly discusses the recent progresses on fluorescent QDs probes and their biological labeling including their surface modification and functionalization.