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中文摘要：
跨膜丝氨酸蛋白酶6（TMPRSS6）是最近发现的一种丝氨酸蛋白激酶,它通过调节铁调素（hepcidin）的表达,进而影响生物机体的铁稳态.它的发现,不仅对进一步认识机体铁代谢的调控及其分子机制有重要的理论意义,还为揭示铁代谢相关疾病的病因和探索治疗的相关途径提供了新的思路.
英文摘要：
Transmenbrance serine proteases 6（TMPRSS6） is a recently identified transmembrane serine protease, this protein regulates the expression of hepcidin in the process of iron metabolism, thereby affecting the body of the iron steady. The discovery of TMPRSS6 is not only very important to the understanding of mechanism of iron metabolism but also reveals the etiology of iron metabolism-related diseases, it provides a new way of thinking about how to treat these diseases.
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Effect of erythropoietin on hepcidin, DMT1 with IRE, and hephaestin gene expression in duodenum of r
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