严重脓毒症和脓毒性休克是在脓毒症基础上并发器官功能衰竭或者组织灌注不足为特征的临床综合征,其病死率高.虽然早期足量快速的液体复苏是严重脓毒症和脓毒性休克治疗的关键,但白蛋白、血浆、红细胞、血小板、丙种球蛋白等血制品输注,以及血液净化、乌司他丁联合胸腺肽和抗CD14单克隆抗体等免疫支持也起着一定作用.
Severe sepsis and septic shock is a clinical syndrome with sequential organ dysfunction or tissue hypoperfusion induce by sepsis. Although early, adequately and rapidly initial resuscitation plays pivotal role in the management, but infusion of albumin, plasma, red blood cell, platelet, gamma globulin and other blood products and the immunological support with ulinastatin combined with thymosin, blood purification and anti CD14 monoclonal antibody therapy also play an important role.