以1,2-二苯基乙二胺和邻羟基苯乙酸以及脯氨酸为原料,设计并合成了咪唑啉-酚,四氢吡咯-咪唑啉两类手性催化剂,初步研究了它们在催化不对称Michael加成反应中的催化活性.
Two kinds of chiral catalysts, imidazoline-phenol and pyrrolidine-imidazoline, were designed and synthesized with 2-hydroxyphenylacetic acid, praline and 1,2-diphenylethylenediamine as the start materials. A preliminary study was made of their activity in catalyzing the asymmetric Michael addition reaction.