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胰腺实性假乳头状瘤^18F—FDGPET/CT影像表现和代谢特征分析
  • ISSN号:2095-2848
  • 期刊名称:《中华核医学与分子影像杂志》
  • 时间:0
  • 分类:R735[医药卫生—肿瘤;医药卫生—临床医学]
  • 作者机构:[1]徐州医学院医学影像学院,221002, [2]第二军医大学长海医院核医学科,上海200433, [3]解放军第四一一医院PET/CT中心,上海200081, [4]宁波大学医学院附属医院影像科,315807
  • 相关基金:国家自然科学基金(81170435);中国博士后基金(20100480545);上海市科委国际合作基金(10410708800)
中文摘要:

目的 总结胰腺实性假乳头状瘤(SPTP)^18F-FDG PET/CT的影像表现和代谢特点,提高对该病的认识和诊断准确性。方法 回顾性分析2010年8月至2014年6月在上海长海医院经病理证实为SPTP的16例患者(男3例,女13例,平均年龄38.6岁)PET/CT及临床资料。观察病灶的形态、密度及代谢特征,测量病灶大小、SUVmax;对10例行双时相显像患者的早期SUVmax与延迟SUVmax进行配对t检验,并计算滞留指数(RI)。结果16例患者病灶均为单发、外生性生长,边界较清楚。肿瘤长径1.2~10.4(4.0±2.7) cm,短径1.0~8.6(3.3±2.2) cm。4例实性病灶中,2例为均匀高代谢灶,1例不均匀高代谢灶,1例FDG摄取与正常胰腺实质相仿;12例囊实性病灶表现为不均匀高代谢区(内见代谢明显增高壁结节)与不规则轻度代谢和(或)摄取缺损区混杂,缺损区可位于肿瘤中心或边缘。16例患者SUVmax为7.3±6.8(2.4~29.1);10例双时相显像患者早期SUVmax为6.0±3.4(2.4~14.1),延迟SUVmax为6.4±3.2(2.3~13.4),差异无统计学意义(t=-1.658, P〉0.05);RI为6.9%(-4.2%,13.6%)。16例中5例病灶侵犯胰管或胰周器官,对应病灶SUVmax为6.7±4.1(3.4~13.1),无侵犯病灶的SUVmax为4.4(2.6,7.6)。结论 SPTP多表现为体积较大、边界清楚、向胰腺外突出且伴有钙化的囊实性或实性肿块。病灶代谢特征多样,实性部分FDG多为高摄取,延迟显像后FDG摄取无明显变化。

英文摘要:

Objective To summarize the imaging features and metabolic characteristics of solid pseudopapillary tumors of the pancreas (SPTP) using ^18F-FDG PET/CT in order to improve the diagnostic accuracy.Methods ^18F-FDG PET/CT findings and clinical data of 16 patients (3 males, 13 females, average age 38.6 years) pathologically proved SPTP from August 2010 to June 2014 in Shanghai Changhai Hospital were analyzed retrospectively. The morphology, density and metabolic characteristics of the lesions were observed, and SUVmax and tumor size were measured and recorded. The difference between early SUVmax and delayed SUVmax was evaluated with paired t test in 10 patients underwent dual-time scans, and the retention index (RI) was also calculated.Results The lesions were all single with well delineated and exogenous growth. The long diameter of the tumors was about 1.2-10.4(4.0±2.7) cm, and the short diameter was 1.0-8.6(3.3±2.2) cm. Four tumors were nearly completely solid, in which 2 lesions showed high and uniform FDG accumulation, 1 inhomogeneous high metabolic lesion, and 1 with FDG uptake similar to normal pancreas. The other 12 cases demonstrated solid and cystic mixed structures which showed uneven high metabolic components in mural nodules mixed with mild metabolic and/or uptake defect. The early SUVmax of all patients was 7.3±6.8(2.4-29.1). For the 10 patients with dual-phase scans, no statistical difference was seen between the early SUVmax (6.0±3.4) and the delayed SUVmax(6.4±3.2)(t=-1.658, P〉0.05); RI was 6.9%(-4.2%, 13.6%). Among the 16 patients, 5 were found to have invasion of pancreatic duct or surrounding organs of pancreas, with early SUVmax (6.7±4.1)(3.4-13.1), SUVmax of remaining 11 patients was 4.4(2.6, 7.6).Conclusions SPTP is mostly cystic-solid or solid lesions with big volumes, calcification, well-defined borders and outward swelling. On FDG PET images, there are diverse metabolic characteristics of lesions, with high uptake on the solid part,

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期刊信息
  • 《中华核医学与分子影像杂志》
  • 中国科技核心期刊
  • 主管单位:中国科学技术协会
  • 主办单位:中华医学会
  • 主编:
  • 地址:江苏省无锡市大娄巷23号
  • 邮编:214002
  • 邮箱:zhhyx@pub.wx.jsinfo.net
  • 电话:0510-82721344 82731904
  • 国际标准刊号:ISSN:2095-2848
  • 国内统一刊号:ISSN:32-1828/R
  • 邮发代号:28-72
  • 获奖情况:
  • 国家“双效”期刊,1987年9月中华医学会颁发优秀杂志三等奖,1992年10月中国科学技术协会颁发首届优秀学术期刊...
  • 国内外数据库收录:
  • 美国化学文摘(网络版),中国中国科技核心期刊,中国北大核心期刊(2011版),中国北大核心期刊(2014版)
  • 被引量:1298